MAPK12 ZEBRAFISH

Name: Mitogen-activated protein kinase 12 - zebrafish

Alternative names: P38gamma, SAPK3, Erk6

Taxonomy: [Danio rerio] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Elopocephala; Clupeocephala; Otocephala; Ostariophysi; Otophysi; Cypriniphysi; Cypriniformes; Cyprinoidea; Cyprinidae; Danio.

Protein Size: 363 aa

mRNA Size: 1756 bp

MW: 41971 Da

pI: 6.81

Activator MKKs: MAP2K3 (MKK3); MAP2K5 (MKK5); MAP2K6 (MKK6)

Activation site: TGY (pThr-181 and pTyr-183)

Protein sequence [FASTA]:

>mkr|DAR000012|MK12_ZEBRAFISH|Mitogen-activated protein kinase 12 
MTARSRPGYFRQEINKTIWEVPDRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPF
QSDLFAKRAYRELRLLKHMKHDNVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKM
ERLSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEECELKILDFGLARQTDSEM
TGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLLGKPLFKGHDHLDQLMEIMKVT
GTPSKEFTAKLQSEDARNYVTKLPRFRKKDLRILLPNVNPQAIKVLDGMLLLDPESRITA
AEALAFPFFSEFREPEEETEAPPYDHSLDEADQSLEQWKRLTFTEILTFQPAPAVAESKE
TAL

Cross references

RefSeq: Protein: NP_571482.1. Nucleotide sequence: NM_131407.1.
NCBI Gene: 30681 [ MAPK12 mitogen-activated protein kinase 12]
UniProtKB: O42376 [ MAPK12 ]