MAPK3 RAT

Name: Mitogen-activated protein kinase 3 - rat

Alternative names: Erk1, p44-MAPK

Taxonomy: [Rattus norvegicus] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

Protein Size: 380 aa

mRNA Size: 1875 bp

MW: 43081 Da

pI: 6.28

Activator MKKs: MAP2K1 (MEK1); MAP2K2 (MEK2)

Activation site: TEY (pThr-203 and pTyr-205)

Protein sequence [FASTA]:

>mkr|RAN000003|MK3_RAT|Mitogen-activated protein kinase 3 
MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSA
YDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVY
IVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCD
LKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML
SNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKS
DSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKER
LKELIFQETARFQPGAPEAP

Cross references

RefSeq: Protein: NP_059043.1. Nucleotide sequence: NM_017347.2.
NCBI Gene: 50689 [ MAPK3 mitogen-activated protein kinase 1 ]
UniProtKB: P21708 [ MAPK3 ]