MAPK4 HUMAN

Name: Mitogen-activated protein kinase 4 - human

Alternative names: Erk4, p63-MAPK, Prkm4

Taxonomy: [Homo sapiens] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo.

Protein Size: 587 aa

mRNA Size: 4736 bp

MW: 65922 Da

pI: 5.25

Activator MKKs: ?

Activation site: SEG (pSer-186)

Protein sequence [FASTA]:

>mkr|HOS000004|MK4_HUMAN|Mitogen-activated protein kinase 4 
MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW

Cross references

RefSeq: Protein: NP_002738.2. Nucleotide sequence: NM_002747.3.
NCBI Gene: 5596 [ MAPK4 mitogen-activated protein kinase 4 ]
UniProtKB: P31152 [ MAPK4 ]
NextProt: NX_P31152 [ Mitogen-activated protein kinase 4 ]
HPRD: 01497 [ MAPK4 ]