MAPK8 MOUSE

Name: Mitogen-activated protein kinase 8 - mouse

Alternative names: JNK1,JNK-46, SAPK1, Prkm8

Taxonomy: [Mus musculus] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.

Protein Size: 384 aa

mRNA Size: 5770 bp

MW: 44229 Da

pI: 7.58

Activator MKKs: MAP2K4 (MKK4};MAP2K5 (MKK5); MAP2K7 (MKK7)

Activation site: TPY (pThr-183 and pTyr-185)

Protein sequence [FASTA]:

>mkr|MUM000008|MK8_MOUSE|Mitogen-activated protein kinase 8 
MSMSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLAQVQQ

Cross references

RefSeq: Protein: NP_057909.1. Nucleotide sequence: NM_002750.2.
NCBI Gene: 26419 [ MAPK8 mitogen-activated protein kinase 8 ]
UniProtKB: Q91Y86 [ MAPK8 ]