MAPK9 HUMAN

Name: Mitogen-activated protein kinase 9 - human

Alternative names: JNK2,JNK-55, SAPK2, Prkm9

Taxonomy: [Homo sapiens] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo.

Protein Size: 424 aa

mRNA Size: 4336 bp

MW: 48139 Da

pI: 5.4

Activator MKKs: MAP2K4 (MKK4};MAP2K5 (MKK5); MAP2K7 (MKK7)

Activation site: TPY (pThr-183 and pTyr-185)

Protein sequence [FASTA]:

>mkr|HOS000009|MK9_HUMAN|Mitogen-activated protein kinase 9 
MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR

Cross references

RefSeq: Protein: NP_002743.3. Nucleotide sequence: NM_002752.4.
RefSeq: Protein: NP_620707.1. Nucleotide sequence: NM_139068.2.
RefSeq: Protein: NP_001128516.1. Nucleotide sequence: NM_001135044.1.
RefSeq: Protein: NP_620708.1. Nucleotide sequence: NM_139069.2.
RefSeq: Protein: NP_620709.1. Nucleotide sequence: NM_139070.2.
NCBI Gene: 5601 [ MAPK9 mitogen-activated protein kinase 9 ]
UniProtKB: P45984 [ MAPK9 ]
NextProt: NX_P45984 [ Mitogen-activated protein kinase 9 ]
HPRD: 3E7O [ JNK2 ]
RCSB PDB: 3NPC [ JNK2 ]